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Another study showed that GLP-1R knockout mice have impaired LTP when compared to control animals ( These previous studies together suggest that GLP-1 may improve memory and cognitive function in patients with depression by enhancing synaptic function and neuronal signal transmission in the brain

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Similar to GLP-1, amylin is a hormone that helps regulate energy consumption by signaling to the brain that the body is full and does not need to eat more, leading to reduced meal size and food intake, according to Wayne Ho, MD, a clinical investigator in diabetes and obesity and a professor at Keck School of Medicine in Los Angeles